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However, age did not exhibit a similar correlation, suggesting that AKR1C3 may serve as a prognostic indicator for poor outcomes among PCa patients ( The cornerstone of treating advanced PCa is androgen-deprivation therapy (ADT), aiming to reduce circulating androgens to castration levels ( de novo testosterone through the upregulation of steroidogenic enzymes, including Cyp17A1, AKR1C3, and 5-reductase

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Fang, X., Ardehali, H., Min, J

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Meanwhile, across two Phase III studies in nr-axSpA and AS, Bimzelx demonstrated statistically significant improvements vs